Increased permeability of the blood-brain barrier after carotid Renografin-76.
نویسندگان
چکیده
Increased permeability or " breakdown " of the bloodbrain barrier following the carotid injection of various contrast media has been previously documented [1 -6]. Trans ient opening of the blood-brain barrier may also be produced by injecting hyperosmotic mannitol or arabinose into th e interna l carotid artery [7 -12]. CT scanning has recently been appli ed to the definition and quantitation of this barri e r breakdown [1 3 , 14]. This case report documents , with crania l c omputed tomography (CT) , disruption of the bloodbra in barri e r after th e intracarotid injection of a hyperosmotic iodinated contrast media.
منابع مشابه
Relationship between dietary virgin Olive oil on brain Cholesterol, Cholesteryl ester and Triglyceride levels and Blood Brain Barrier (BBB) permeability in a rat stroke model
Introduction: Recent studies suggest that dietary virgin olive oil (VOO) reduces hypoxia-re oxygenation injury in rat brain. We have attempted to determine the effect of dietary virgin olive oil on brain lipidomics and its relationship with brain edema in a rat stroke model. Methods: Five groups, each consisting of 6 male Wistar rats, were studied. The first and second groups (control and s...
متن کاملP 19: The Effects of Aloe Vera Extract on Brain Edema and Blood-Brain Barrier Permeability after Traumatic Brain Injury
Introduction: Recent studies have reported that the Aloe vera (Aloe barbadensis miller) plant has anti-inflammatory and antioxidant effects. This study evaluated the neuroprotective effects of different doses of Aloe vera extract after traumatic brain injury (TBI) in male rats. Materials and Methods: In this study, 70 male rats were divided into 2 groups; each group consists of 5 of sub-g...
متن کاملIntensification of brain injury and blood-brain barrier permeability by short-term hypertension in experimental model of brain ischemia/reperfusion
Introduction: Arterial hypertension is one of the causes of stroke, and as one of the vasculotoxic conditions intensifies ischemic stroke complications. The aim of the present study was to analyze the effects of short-term cerebral hypertension on ischemia/reperfusion injury and pathogenesis of ischemic stroke. Methods: The experiments were performed on three groups of rats (N=36) Sham, cont...
متن کاملبررسی اثر انسداد گذرای شریان مرکزی در کاهش آسیب‌های مغزی در مدل سکته‌ی مغزی رت
Background and Objective: Recent studies suggest that sub-lethal ischemia protect the brain from subsequent ischemic injuries. This study was an effort to identify and shed light on the nature of changes in the blood brain barrier permeability and brain edema. Materials and Methods: Rats were divided into four main experimental groups, each of 21 animals. The first group acted as a model of isc...
متن کاملEffect of Nesfatin-1 on Permeability of Blood Brain Barrier, Neurological Score and Brain Edema after Traumatic Brain Injury in Male Rats: A Behavioral and Biochemical Study
Background and purpose: Traumatic brain injury (TBI) is one of the most complex diseases of the central nervous system (CNS). Nesfatin is an 82-amino acid effective polypeptide in CNS. In this study, we investigated the role of nesfatin in neuron protection in the process of diffuse concussion in rats and also its effect on the level of matrix metalloproteinase-9. Materials and methods: In thi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 2 3 شماره
صفحات -
تاریخ انتشار 1981